Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GSDMD | P57764 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.31 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3910063 | 0.72 | LMNA (0.48) | TSHRABCB11HTTGSDMDEHMT2 | |
| SCHEMBL3910061 | 0.72 | LMNA (0.48) | TSHRABCB11HTTGSDMDEHMT2 | |
| SCHEMBL3913645 | 0.72 | LMNA (0.48) | TSHRABCB11HTTGSDMDEHMT2 | |
| SCHEMBL8440401 | 0.67 | — | — | |
| SCHEMBL8474938 | 0.67 | EHMT2 (0.33) | TSHRTDP1ABCB11CYP2E1PTGS1 | |
| SCHEMBL122748 | 0.65 | — | — | |
| SCHEMBL7528871 | 0.65 | — | — | |
| SCHEMBL7526128 | 0.65 | — | — | |
| SCHEMBL10391701 | 0.65 | LMNA (0.36) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL8057917 | 0.64 | TSHR (0.44) | TSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012804-B1 | Salts of a non toxic, activated anion exchange resin capable of establishing a stable binding with bile acids and 2-(4'-(p-chlorobenzoyl)-phenoxy)-2-(methyl)-propionic acid and pharmaceutical compositions comprising these salts | ALFA FARMACEUTICI S.p.A. (IT) | 1981-12-30 | — | — | EP | claimed |
| US-4340585-A | Salified anionic resin for cholesterol and lipid lowering | ALFA FARMACEUTICI, S.P.A. (IT) | 1982-07-20 | — | — | US | disclosed |