Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15007062 | 0.92 | TSHR (0.58) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL15007063 | 0.87 | TSHR (0.50) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL11890619 | 0.85 | USP2 (0.57) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL10872413 | 0.84 | THRB (0.50) | TSHRTHRBMEN1KMT2AALDH1A1 | |
| SCHEMBL28094183 | 0.84 | USP2 (0.56) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL15007008 | 0.83 | TSHR (0.46) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL2853366 | 0.83 | USP2 (0.60) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL13966358 | 0.83 | USP2 (0.60) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL4201207 | 0.83 | TSHR (0.50) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL12821078 | 0.82 | HTT (0.52) | TSHRHTTTHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006627-B1 | RADIATION-SENSITIVE MIXTURE AND PROCESS FOR PRODUCING RELIEF IMAGES | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-05-18 | — | — | EP | disclosed |
| US-4248957-A | ENOL ETHER CONTAINING COMPOUND OF WHICH THE SOLUBILITY IN DEVELOPER INCREASES ON CLEAVAGE | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-02-03 | — | — | US | disclosed |
| EP-0006627-A2 | Radiation-sensitive mixture and process for producing relief images | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-09 | — | — | EP | disclosed |