Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23782426 | 0.84 | BCL2L1 (0.57) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23792167 | 0.80 | BCL2L1 (0.53) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11232580 | 0.80 | STING1 (0.66) | BCL2L1STING1 | |
| SCHEMBL5161323 | 0.78 | BCL2L1 (0.57) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6334117 | 0.76 | BCL2L1 (0.62) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28118458 | 0.74 | BCL2L1 (0.65) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12123735 | 0.73 | BCL2L1 (0.59) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9602069 | 0.72 | BCL2L1 (0.62) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL231135 | 0.72 | BCL2L1 (0.62) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1574615 | 0.72 | BCL2L1 (0.62) | BCL2L1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342689-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| US-4342690-A | HHYPOTENSIVE AGE TS | AMERICAN CYANAMID COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| US-4342691-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| US-4299769-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-11-10 | — | — | US | disclosed |