Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 5/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10784071 | 0.86 | BCL2L1 (0.59) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28118458 | 0.84 | BCL2L1 (0.65) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL231135 | 0.82 | BCL2L1 (0.62) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10313792 | 0.82 | BCL2L1 (0.62) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6334117 | 0.82 | BCL2L1 (0.62) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6121585 | 0.81 | GSK3B (0.55) | GSK3B | |
| Hydrochloric Acid SCHEMBL4918686 | 0.81 | BCL2L1 (0.61) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11575531 | 0.81 | BCL2L1 (0.61) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9585720 | 0.81 | BCL2L1 (0.66) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL103529 | 0.79 | BCL2L1 (0.69) | BCL2L1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8618133-B2 | Aralkyl alcohol pyridine derivative compounds and the use thereof as medicaments for treating depression | JIANGSU HENGYI PHARMACEUTICAL CO., LTD. (CN) | 2013-12-31 | — | — | US | disclosed |
| CN-101602708-B | Aryl alkanol piperidine derivative and application thereof as antidepressive medicine | JIANGSU GUOHUA INVEST CO LTD | 2012-11-21 | — | — | CN | disclosed |
| US-20110160247-A1 | Aralkyl alcohol piperidine derivative and the use thereof as a medicament for treating depression | JIANGSU GOWORTH INVESTMENT CO. LTD (CN) | 2011-06-30 | — | — | US | disclosed |
| EP-2305644-A1 | ARALKYL ALCOHOL PIPERIDINE DERIVATIVE AND THE USE AS MEDICAMENT FOR TREATING DEPRESSION THEREOF | Jiangsu Goworth Investment Co. Ltd (CN) | 2011-04-06 | — | — | EP | disclosed |
| CN-101602708-A | Aralkyl alcohol piperidine derivative and as the application of anti-depression drug | JIANGSU GUOHUA INVEST CO LTD (CN) | 2009-12-16 | — | — | CN | disclosed |
| US-5679678-A | ANALGESIC AND ANTIINFLAMMATORY AGENTS | CHEMISCH PHARMAZEUTISCHE FORSCHUNGSGESELLSCHAFT M.B.H. (AT) | 1997-10-21 | — | — | US | disclosed |
| EP-0658559-A1 | Thienothiazin derivatives, process for their preparation and their use as 5-dipoxygenase and cyclooxygenase inhibitors | Chemisch Pharmazeutische Forschungsgesellschaft m.b.H. (AT) | 1995-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160247-A1 | Aralkyl alcohol piperidine derivative and the use thereof as a medicament for treating depression | DRD4, DRD5, DRD3 | BCL2L1 811/4885HDAC3 937/4885HDAC4 364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.