SCHEMBL11224489

SCHEMBL11224489

CC1([C@H]2CC[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4CC[C@]23C)OO1

nearest known ligand 0.69

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 14/20 0.69
CYP3A4 P08684 1/20 0.60
LMNA P02545 2/20 0.58
MAPT P10636 2/20 0.58
SHBG P04278 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12029055 0.91 CYP19A1 (0.67) CYP19A1CYP3A4LMNAMAPTSHBG
SCHEMBL14046282 0.83 CYP19A1 (0.76) CYP19A1CYP3A4LMNAMAPTSHBG
SCHEMBL13259634 0.83 CYP19A1 (0.62) CYP19A1CYP3A4LMNAMAPTSHBG
SCHEMBL11020843 0.82 CYP19A1 (1.00) CYP19A1CYP3A4LMNAMAPTSHBG
SCHEMBL13994334 0.82 CYP19A1 (0.74) CYP19A1CYP3A4LMNAMAPT
SCHEMBL13752636 0.82 CYP19A1 (1.00) CYP19A1CYP3A4LMNAMAPTSHBG
SCHEMBL13001778 0.82 CYP19A1 (1.00) CYP19A1CYP3A4LMNAMAPTSHBG
SCHEMBL13787743 0.82 CYP19A1 (1.00) CYP19A1CYP3A4LMNAMAPTSHBG
SCHEMBL15903 0.82 CYP19A1 (1.00) CYP19A1CYP3A4LMNAMAPTSHBG
SCHEMBL12430769 0.82 CYP19A1 (1.00) CYP19A1CYP3A4LMNAMAPTSHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57088200-A None JP disclosed
JP-S5788200-A SYNTHETIC INTERMEDIATE OF CORTICOIDS MITSUBISHI CHEM IND LTD 1982-06-01 JP disclosed