Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12029055 | 0.85 | CYP19A1 (0.67) | CYP19A1LMNAMAPTCYP3A4SHBG | |
| SCHEMBL11224489 | 0.83 | CYP19A1 (0.69) | CYP19A1LMNAMAPTCYP3A4SHBG | |
| SCHEMBL8980363 | 0.79 | CYP19A1 (0.72) | CYP19A1LMNAMAPTCYP3A4 | |
| SCHEMBL28095059 | 0.78 | CYP19A1 (0.76) | CYP19A1LMNAMAPTCYP3A4SHBG | |
| SCHEMBL14046282 | 0.78 | CYP19A1 (0.76) | CYP19A1LMNAMAPTCYP3A4SHBG | |
| Fluoride SCHEMBL29039527 | 0.78 | CYP19A1 (0.71) | CYP19A1LMNAMAPTCYP3A4SHBG | |
| SCHEMBL4431797 | 0.77 | CYP19A1 (1.00) | CYP19A1LMNAMAPTCYP3A4SHBG | |
| SCHEMBL13787743 | 0.77 | CYP19A1 (1.00) | CYP19A1LMNAMAPTCYP3A4SHBG | |
| SCHEMBL13001778 | 0.77 | CYP19A1 (1.00) | CYP19A1LMNAMAPTCYP3A4SHBG | |
| SCHEMBL15903 | 0.77 | CYP19A1 (1.00) | CYP19A1LMNAMAPTCYP3A4SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010088409-A2 | METHODS OF NEUROPROTECTION USING NEUROPROTECTIVE STEROIDS AND A VITAMIN D | EMORY UNIVERSITY (US) | 2010-08-05 | — | — | WO | disclosed |