Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.46 |
| ▸ | USP7 | Q93009 | 4/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | QDPR | P09417 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11154766 | 0.99 | ESR1 (0.45) | ESR1ESR2USP7MAPK14QDPR | |
| Bromide SCHEMBL1841795 | 0.99 | ESR1 (0.45) | ESR1ESR2USP7MAPK14QDPR | |
| SCHEMBL15487431 | 0.88 | MAPK14 (0.49) | ESR1ESR2USP7MAPK14HSP90AA1 | |
| Hydrochloric Acid SCHEMBL15486032 | 0.87 | MAPK14 (0.48) | ESR1ESR2USP7MAPK14HSP90AA1 | |
| SCHEMBL20134950 | 0.82 | HTR3A (0.41) | MAPK14HTR1F | |
| SCHEMBL187372 | 0.82 | SCD (0.51) | SCD | |
| SCHEMBL29688619 | 0.82 | SCD (0.51) | SCD | |
| SCHEMBL29688952 | 0.82 | HTR3A (0.41) | MAPK14HTR1F | |
| SCHEMBL14034032 | 0.82 | HTR2A (0.46) | MAPK14HTR1AHTR1FSCD | |
| Hydrochloric Acid SCHEMBL23581610 | 0.81 | HTR2A (0.45) | MAPK14HTR1AHTR1FSCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4355037-A | ANALGESICS | HOECHST-ROUSSEL PHARMACEUTICALS (US) | 1982-10-19 | — | — | US | claimed |