Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.48 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP24A1 | Q07973 | 4/20 | 0.42 |
| ▸ | CYP27B1 | O15528 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4173552 | 0.80 | CYP19A1 (0.42) | CYP19A1CYP26A1CYP3A4SLC6A3ALDH1A1 | |
| SCHEMBL9558665 | 0.77 | CYP3A4 (0.63) | CYP19A1CYP26A1CYP3A4KMT2AMEN1 | |
| SCHEMBL3560288 | 0.76 | CYP19A1 (0.61) | CYP19A1CYP26A1CYP3A4KMT2AMEN1 | |
| SCHEMBL11243475 | 0.75 | CYP19A1 (0.51) | CYP19A1CYP26A1CYP3A4KMT2AMEN1 | |
| SCHEMBL11333169 | 0.75 | CYP19A1 (0.52) | CYP19A1CYP26A1CYP3A4KMT2AMEN1 | |
| SCHEMBL3558863 | 0.75 | CYP26A1 (0.57) | CYP19A1CYP26A1CYP3A4KMT2AMEN1 | |
| SCHEMBL2546988 | 0.75 | CYP19A1 (0.55) | CYP19A1CYP26A1CYP3A4KMT2AMEN1 | |
| SCHEMBL410235 | 0.74 | CYP19A1 (0.56) | CYP19A1CYP26A1CYP3A4KMT2AMEN1 | |
| SCHEMBL10564669 | 0.74 | CYP19A1 (0.53) | CYP19A1CYP26A1CYP3A4KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9996070 | 0.72 | CYP19A1 (0.54) | CYP19A1CYP26A1CYP3A4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4351948-A | Imidazole hydrazone derivatives | G.D. SEARLE & CO. (US) | 1982-09-28 | — | — | US | disclosed |