Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.61 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP24A1 | Q07973 | 4/20 | 0.47 |
| ▸ | CYP27B1 | O15528 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17315106 | 0.85 | CYP19A1 (0.61) | CYP19A1CYP26A1CYP3A4MEN1ADRA1A | |
| SCHEMBL2546988 | 0.82 | CYP19A1 (0.55) | CYP19A1CYP26A1CYP3A4MEN1ADORA3 | |
| SCHEMBL9558665 | 0.82 | CYP3A4 (0.63) | CYP19A1CYP26A1CYP3A4MEN1ADORA3 | |
| SCHEMBL9523337 | 0.82 | CYP19A1 (0.55) | CYP19A1CYP26A1CYP3A4MEN1ADORA3 | |
| SCHEMBL3558863 | 0.82 | CYP26A1 (0.57) | CYP19A1CYP26A1CYP3A4MEN1ADORA3 | |
| SCHEMBL11333169 | 0.80 | CYP19A1 (0.52) | CYP19A1CYP26A1CYP3A4MEN1ADORA3 | |
| SCHEMBL3555929 | 0.78 | HSD17B10 (0.58) | CYP19A1CYP3A4MEN1ADORA3KMT2A | |
| SCHEMBL11224914 | 0.76 | CYP19A1 (0.48) | CYP19A1CYP26A1CYP3A4MEN1ADORA3 | |
| SCHEMBL10693298 | 0.76 | CYP19A1 (1.00) | CYP19A1CYP26A1CYP3A4MEN1ADRA1A | |
| SCHEMBL11774887 | 0.76 | CYP19A1 (0.54) | CYP19A1CYP26A1CYP3A4MEN1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727998-B2 | Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |
| US-20060106046-A1 | Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient | MSD K.K. (JP) | 2006-05-18 | — | — | US | disclosed |
| EP-1595867-A1 | MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISTS CONTAINING PIPERIDINE DERIVATIVES AS THE ACTIVE INGREDIENT | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106046-A1 | Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient | MCHR1, MC1R, PRLHR | CYP19A1 156/4885CYP26A1 447/4885CYP3A4 1270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.