⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29700378 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL30162773 | 0.97 | TSHR (0.52) | — | |
| Hydrochloric Acid SCHEMBL907224 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL320817 | 0.80 | — | — | |
| SCHEMBL928091 | 0.80 | — | — | |
| SCHEMBL12480566 | 0.80 | TSHR (0.50) | — | |
| Hydrochloric Acid SCHEMBL17023694 | 0.78 | TSHR (0.48) | — | |
| SCHEMBL17649942 | 0.76 | TSHR (0.40) | — | |
| SCHEMBL31413032 | 0.73 | TSHR (0.37) | — | |
| SCHEMBL8166926 | 0.72 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1583 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079857-A | Synthesis method of 6-chloro-7-fluoroisatin | — | 2026-05-26 | — | — | CN | claimed |
| CN-120040358-A | Preparation method and application of quinazoline derivative containing chalcone | 沈阳工业大学 | 2025-05-27 | — | — | CN | claimed |
| CN-119707773-A | Preparation method and application of maleimide structure-containing compound | 中国农业大学 | 2025-03-28 | — | — | CN | claimed |
| US-11866391-B2 | Anesthetic compounds and methods of making and using same to treat or prevent pain symptoms | PTC Innovations, LLC (US) | 2024-01-09 | — | — | US | claimed |
| US-20230399290-A1 | ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS | PTC INNOVATIONS LLC (US) | 2023-12-14 | — | — | US | claimed |
| CN-116239577-A | Method for preparing cudexestat | 沈阳药科大学 | 2023-06-09 | — | — | CN | claimed |
| CN-110590683-B | Preparation method of intermediate of targeting drug AZD3759 | 山东四环药业股份有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-111675700-A | Preparation method of novel anti-cancer drug AZD3759 | 通化师范学院 | 2020-09-18 | — | — | CN | claimed |
| CN-111662273-A | Preparation method of tyrosine kinase inhibitor AZD3759 | 通化师范学院 | 2020-09-15 | — | — | CN | claimed |
| CN-107400088-B | 1, 3-disubstituted pyrazole derivatives, and preparation method and application thereof | 山东大学 | 2020-04-28 | — | — | CN | claimed |
| EP-1667996-A1 | QUINAZOLINE DERIVATIVES | Astrazeneca AB (SE) | 2006-06-14 | — | — | EP | claimed |
| EP-1664030-A1 | QUINAZOLINE DERIVATIVES | AstraZeneca AB (SE) | 2006-06-07 | — | — | EP | claimed |
| EP-1622620-A1 | QUINAZOLINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER | AstraZeneca AB (SE) | 2006-02-08 | — | — | EP | claimed |
| WO-2006012642-A2 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS, INC. (US) | 2006-02-02 | — | — | WO | claimed |
| WO-2005075439-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-08-18 | — | — | WO | claimed |
| WO-2005026156-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-03-24 | — | — | WO | claimed |
| WO-2005026150-A1 | QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2005-03-24 | — | — | WO | claimed |
| WO-2005026157-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-03-24 | — | — | WO | claimed |
| WO-2004096226-A1 | QUINAZOLINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2004-11-11 | — | — | WO | claimed |
| CN-1515539-A | Preparation method of chlorofluoronitrobenzene and derivatives thereof | 解卫宇 | 2004-07-28 | — | — | CN | claimed |