Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6427975 | 0.83 | PPP5C (0.31) | — | |
| SCHEMBL19985884 | 0.78 | GBA1 (0.31) | — | |
| SCHEMBL10962714 | 0.74 | CYP3A4 (0.35) | — | |
| SCHEMBL19211909 | 0.74 | CYP19A1 (0.32) | — | |
| SCHEMBL19985885 | 0.72 | — | — | |
| SCHEMBL5954153 | 0.72 | — | — | |
| SCHEMBL7679321 | 0.72 | — | — | |
| SCHEMBL7451800 | 0.71 | ALDH1A1 (0.40) | — | |
| SCHEMBL13886391 | 0.71 | ALDH1A1 (0.40) | — | |
| SCHEMBL16751992 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309348-A | DIURETICS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |
| US-4235901-A | TREATING HYPERTENSION IN MAMMALS WITH AN EFFECTIVE RENAL MINERALCORTICOID ANTAGONIST | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-11-25 | — | — | US | disclosed |
| US-4179503-A | DIURETICS | AMERICAN HOME PRODUCTS CORP. (US) | 1979-12-18 | — | — | US | disclosed |
| WO-1979001037-A1 | 1-HYDROXYALKANAMINE PYRANO(3,4-B)INDOLE DERIVATIVES | AMERICAN HOME PROD (US) | 1979-11-29 | — | — | WO | disclosed |
| EP-0005365-A1 | Pyrano and thiopyrano (3,4-b) indole derivatives, processes for their preparation and pharmaceutical compositions containing them | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-11-14 | — | — | EP | disclosed |