Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.64 |
| ▸ | ECE1 | P42892 | 8/20 | 0.63 |
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | MME | P08473 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11225545 | 1.00 | ACE (0.64) | ACEECE1LTA4HALOX15MME | |
| Hydrochloric Acid SCHEMBL11235229 | 0.99 | ACE (0.63) | ACEECE1LTA4HALOX15MME | |
| Hydrochloric Acid SCHEMBL11220969 | 0.99 | ACE (0.63) | ACEECE1LTA4HALOX15MME | |
| Hydrochloric Acid SCHEMBL11220975 | 0.99 | ACE (0.63) | ACEECE1LTA4HALOX15MME | |
| SCHEMBL30053206 | 0.96 | ACE (0.61) | ACEECE1LTA4HMMEOPRM1 | |
| SCHEMBL30050967 | 0.95 | ACE (0.68) | ACEECE1ALOX15 | |
| SCHEMBL31220181 | 0.95 | CASP1 (0.60) | ACEECE1LTA4HALOX15MME | |
| SCHEMBL30093097 | 0.93 | ACE (0.66) | ACEECE1ALOX15 | |
| SCHEMBL30093080 | 0.93 | ACE (0.66) | ACEECE1ALOX15 | |
| SCHEMBL30786597 | 0.93 | ECE1 (0.59) | ACEECE1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356118-A | Tryptophan derivatives | G. D. SEARLE & CO. (US) | 1982-10-26 | — | — | US | disclosed |