Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11226156 | 0.88 | TSHR (0.36) | SMN1; SMN2TSHRALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL11228783 | 0.87 | PHGDH (0.37) | SMN1; SMN2TSHRALDH1A1KDM4ELMNA | |
| SCHEMBL11228781 | 0.87 | PHGDH (0.37) | SMN1; SMN2TSHRALDH1A1KDM4ELMNA | |
| SCHEMBL11235406 | 0.86 | MAPT (0.44) | SMN1; SMN2TSHRALDH1A1L3MBTL1CRHBP | |
| SCHEMBL11220832 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRALDH1A1KDM4EHTT | |
| SCHEMBL11220830 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRALDH1A1KDM4EHTT | |
| SCHEMBL11221192 | 0.81 | MAPT (0.44) | SMN1; SMN2ALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL11221194 | 0.81 | MAPT (0.44) | SMN1; SMN2ALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL11226260 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRALDH1A1KDM4EHTT | |
| SCHEMBL11280200 | 0.76 | TSHR (0.44) | SMN1; SMN2TSHRALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358606-A | Esters of phenalkyloxycarbonylamino acids | ZOECON CORPORATION (US) | 1982-11-09 | — | — | US | disclosed |