Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11280199 | 1.00 | TSHR (0.44) | TSHRSMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL11220830 | 0.81 | SMN1; SMN2 (0.52) | TSHRSMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL11220832 | 0.81 | SMN1; SMN2 (0.52) | TSHRSMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL11226263 | 0.76 | SMN1; SMN2 (0.48) | TSHRSMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL11226260 | 0.75 | SMN1; SMN2 (0.47) | TSHRSMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL11232835 | 0.73 | TSHR (0.39) | TSHRSMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL11232836 | 0.73 | TSHR (0.39) | TSHRSMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL11235712 | 0.72 | NPC1 (0.49) | SMN1; SMN2ALDH1A1KMT2AMAPTGAA | |
| SCHEMBL11235694 | 0.72 | NPC1 (0.49) | SMN1; SMN2ALDH1A1KMT2AMAPTGAA | |
| SCHEMBL4154989 | 0.72 | TSHR (0.46) | TSHRSMN1; SMN2ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358606-A | Esters of phenalkyloxycarbonylamino acids | ZOECON CORPORATION (US) | 1982-11-09 | — | — | US | disclosed |