SCHEMBL11226795

SCHEMBL11226795

CC(C)(c1ccccc1)c1ccc(O)c(-c2ccccc2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 4/20 0.60
CNR2 P34972 4/20 0.60
ESR1 P03372 6/20 0.55
ESR2 Q92731 5/20 0.55
ALDH1A1 P00352 2/20 0.55
CYP3A4 P08684 2/20 0.55
BACE1 P56817 2/20 0.52
KLF10 Q13118 1/20 0.49
HPGD P15428 2/20 0.45
HSD17B10 Q99714 2/20 0.45
BCL2L1 Q07817 1/20 0.45
PELI1 Q96FA3 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
AR P10275 1/20 0.42
TSHR P16473 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
HTR6 P50406 1/20 0.42
ESRRG P62508 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13609955 0.98 CNR1 (0.58) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL29602069 0.96 BACE1 (0.56) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL136305 0.96 BACE1 (0.56) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL29375340 0.96 BACE1 (0.56) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL25404377 0.95 CNR1 (0.59) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL8422985 0.93 ESR1 (0.61) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL7117740 0.90 CNR1 (0.50) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL7653909 0.87 CNR1 (0.48) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL822109 0.86 ESR1 (0.53) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL835714 0.86 ESR1 (0.66) CNR1CNR2ESR1ESR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57080439-A None JP disclosed
JP-S5780439-A FLAME RETARDANT SANKO KAIHATSU KAGAKU KENKYUSHO:KK 1982-05-20 JP disclosed