Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11226830 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2TSHRKMT2APOLBKDM4E | |
| SCHEMBL11264173 | 0.92 | IDO1 (0.44) | SMN1; SMN2TSHRKDM4EPTGDR2LMNA | |
| SCHEMBL11220832 | 0.87 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRKMT2AKDM4EPTGDR2 | |
| SCHEMBL11220830 | 0.87 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRKMT2AKDM4EPTGDR2 | |
| SCHEMBL11228783 | 0.84 | PHGDH (0.37) | SMN1; SMN2TSHRKDM4EPTGDR2LMNA | |
| SCHEMBL11228781 | 0.84 | PHGDH (0.37) | SMN1; SMN2TSHRKDM4EPTGDR2LMNA | |
| SCHEMBL11232835 | 0.82 | TSHR (0.39) | SMN1; SMN2TSHRKMT2APOLBPTGDR2 | |
| SCHEMBL11232836 | 0.82 | TSHR (0.39) | SMN1; SMN2TSHRKMT2APOLBPTGDR2 | |
| SCHEMBL11221455 | 0.81 | KMT2A (0.51) | SMN1; SMN2KMT2APOLBKDM4EMMP12 | |
| SCHEMBL11221450 | 0.81 | KMT2A (0.51) | SMN1; SMN2KMT2APOLBKDM4EMMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358606-A | Esters of phenalkyloxycarbonylamino acids | ZOECON CORPORATION (US) | 1982-11-09 | — | — | US | disclosed |