Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11226832 | 0.92 | SMN1; SMN2 (0.39) | IDO1PTGDR2KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL11226830 | 0.92 | SMN1; SMN2 (0.39) | IDO1PTGDR2KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL11220830 | 0.87 | SMN1; SMN2 (0.52) | PTGDR2KDM4ETSHRSMN1; SMN2MAOB | |
| SCHEMBL11220832 | 0.87 | SMN1; SMN2 (0.52) | PTGDR2KDM4ETSHRSMN1; SMN2MAOB | |
| SCHEMBL11226746 | 0.82 | IDO1 (0.45) | IDO1PTGDR2KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL11221450 | 0.81 | KMT2A (0.51) | IDO1KDM4ESMN1; SMN2MAOBMAPT | |
| SCHEMBL11221455 | 0.81 | KMT2A (0.51) | IDO1KDM4ESMN1; SMN2MAOBMAPT | |
| SCHEMBL11235712 | 0.81 | NPC1 (0.49) | SMN1; SMN2MAOBLMNAMAPT | |
| SCHEMBL11235694 | 0.81 | NPC1 (0.49) | SMN1; SMN2MAOBLMNAMAPT | |
| SCHEMBL11232836 | 0.79 | TSHR (0.39) | PTGDR2TSHRSMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358606-A | Esters of phenalkyloxycarbonylamino acids | ZOECON CORPORATION (US) | 1982-11-09 | — | — | US | disclosed |