SCHEMBL11228009

SCHEMBL11228009

CC(Nc1cccc2ccccc12)OCCO

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
KDM4E B2RXH2 5/20 0.45
HPGD P15428 3/20 0.45
GAA P10253 3/20 0.45
TSHR P16473 2/20 0.45
CA12 O43570 2/20 0.45
CA14 Q9ULX7 2/20 0.45
CA2 P00918 1/20 0.45
MMP2 P08253 1/20 0.45
MMP9 P14780 1/20 0.45
MMP8 P22894 1/20 0.45
MMP14 P50281 1/20 0.45
MAPT P10636 1/20 0.45
HSD17B10 Q99714 1/20 0.45
CYP1A2 P05177 1/20 0.43
CYP2C19 P33261 1/20 0.43
LMNA P02545 1/20 0.40
KMT2A Q03164 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
USP2 O75604 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11222868 0.81 ALDH1A1 (0.41) ALDH1A1KDM4EHPGDTSHRCA12
SCHEMBL4970622 0.76 CA12 (0.51) ALDH1A1KDM4EHPGDGAATSHR
SCHEMBL4970631 0.76 CA12 (0.51) ALDH1A1KDM4EHPGDGAATSHR
SCHEMBL9771724 0.74 SMN1; SMN2 (0.36) ALDH1A1HPGDTSHRMAPTCYP1A2
SCHEMBL11336488 0.73 CA12 (0.56) ALDH1A1KDM4EHPGDGAATSHR
SCHEMBL28930248 0.73 CASR (0.44) ALDH1A1CYP1A2CYP2C19HTR1BHTR1D
SCHEMBL32575454 0.73 IDO1 (0.55) ALDH1A1KDM4EHPGDGAATSHR
SCHEMBL729010 0.73 IDO1 (0.55) ALDH1A1KDM4EHPGDGAATSHR
SCHEMBL7693893 0.71 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDGAATSHR
SCHEMBL9987427 0.70 CA12 (0.49) ALDH1A1KDM4EHPGDGAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4324721-A 1-(4-Alkylaminonaphthylazo)-4-nitrobenzene disperse dyes E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-04-13 US disclosed
US-4054560-A 1-(4-Acyloxyalkylaminonaphthylazo)-4-nitrobenzene disperse dyes E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-10-18 US disclosed