SCHEMBL11228012

SCHEMBL11228012

OCCOCCNc1cccc2ccccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.64
KDM4E B2RXH2 4/20 0.64
TSHR P16473 3/20 0.64
GAA P10253 3/20 0.64
HPGD P15428 3/20 0.64
HSD17B10 Q99714 2/20 0.64
MAPT P10636 2/20 0.64
CA12 O43570 2/20 0.56
CA4 P22748 2/20 0.56
CA7 P43166 2/20 0.56
CA9 Q16790 2/20 0.56
CA14 Q9ULX7 2/20 0.56
CA3 P07451 1/20 0.56
CA6 P23280 1/20 0.56
CA5A P35218 1/20 0.56
CA5B Q9Y2D0 1/20 0.56
RECQL P46063 1/20 0.54
KCNH3 Q9ULD8 2/20 0.48
HTR1D P28221 1/20 0.44
HTR1B P28222 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18080689 0.90 KDM4E (0.49) ALDH1A1KDM4ETSHRGAAHPGD
SCHEMBL6753421 0.83 ALDH1A1 (0.77) ALDH1A1KDM4ETSHRGAAHPGD
SCHEMBL11222875 0.80 CA12 (0.51) ALDH1A1KDM4ETSHRGAAHPGD
SCHEMBL11111574 0.80 ALDH1A1 (0.90) ALDH1A1KDM4ETSHRGAAHPGD
SCHEMBL11283741 0.78 CA12 (0.77) ALDH1A1KDM4ETSHRGAAHPGD
SCHEMBL26421926 0.78 CA12 (0.61) ALDH1A1KDM4ETSHRGAAHPGD
SCHEMBL30471934 0.77 KDM4E (0.97) ALDH1A1KDM4ETSHRGAAHPGD
Hydrochloric Acid SCHEMBL4443499 0.77 ALDH1A1 (0.78) ALDH1A1KDM4ETSHRGAAHPGD
SCHEMBL8065387 0.75 MEN1 (0.49) ALDH1A1KDM4EGAAHPGDMAPT
SCHEMBL6750378 0.75 ALDH1A1 (0.65) ALDH1A1KDM4ETSHRGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4324721-A 1-(4-Alkylaminonaphthylazo)-4-nitrobenzene disperse dyes E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-04-13 US disclosed
US-4054560-A 1-(4-Acyloxyalkylaminonaphthylazo)-4-nitrobenzene disperse dyes E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-10-18 US disclosed