Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2976961 | 1.00 | NPC1 (0.50) | NPC1ACHELMNAEPHX2SMN1; SMN2 | |
| SCHEMBL5236196 | 1.00 | NPC1 (0.50) | NPC1ACHELMNAEPHX2SMN1; SMN2 | |
| SCHEMBL15362702 | 1.00 | NPC1 (0.50) | NPC1ACHELMNAEPHX2SMN1; SMN2 | |
| SCHEMBL14359727 | 0.97 | NPC1 (0.46) | NPC1ACHELMNAEPHX2SMN1; SMN2 | |
| SCHEMBL28236249 | 0.93 | NPC1 (0.45) | NPC1ACHELMNAEPHX2SMN1; SMN2 | |
| SCHEMBL22414144 | 0.93 | NPC1 (0.45) | NPC1ACHELMNAEPHX2SMN1; SMN2 | |
| SCHEMBL18330523 | 0.92 | — | — | |
| SCHEMBL9958288 | 0.91 | NPC1 (0.44) | NPC1ACHELMNAEPHX2SMN1; SMN2 | |
| SCHEMBL11350663 | 0.91 | NPC1 (0.42) | NPC1EPHX2CA2 | |
| SCHEMBL3152054 | 0.89 | NPC1 (0.42) | NPC1LMNAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317942-A | Odoriferous 2-alkoxyethyl-cycloalkyl-ethers | CHEMISCHE WERKE HUELS, AKTIENGESELLSCHAFT (DE) | 1982-03-02 | — | — | US | disclosed |
| EP-0022462-B1 | 2-ALKOXYETHYL-CYCLOALKYL-ETHERS, COMPOSITIONS CONTAINING THESE, AND THEIR UTILIZATION FOR THE PREPARATION OF ODORANT COMPOSITIONS | CHEMISCHE WERKE HÜLS AG (DE) | 1981-11-25 | — | — | EP | disclosed |
| EP-0022462-A1 | 2-Alkoxyethyl-cycloalkyl-ethers, compositions containing these, and their utilization for the preparation of odorant compositions | CHEMISCHE WERKE HÜLS AG (DE) | 1981-01-21 | — | — | EP | disclosed |