SCHEMBL14359727

SCHEMBL14359727

COCCOC1CCCC1

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.46
LMNA P02545 1/20 0.32
EPHX2 P34913 1/20 0.32
ACHE P22303 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11228022 0.97 NPC1 (0.50) NPC1LMNAEPHX2ACHESMN1; SMN2
SCHEMBL15362702 0.97 NPC1 (0.50) NPC1LMNAEPHX2ACHESMN1; SMN2
SCHEMBL5236196 0.97 NPC1 (0.50) NPC1LMNAEPHX2ACHESMN1; SMN2
SCHEMBL2976961 0.97 NPC1 (0.50) NPC1LMNAEPHX2ACHESMN1; SMN2
SCHEMBL18330523 0.95
SCHEMBL11350663 0.93 NPC1 (0.42) NPC1EPHX2
SCHEMBL22414144 0.91 NPC1 (0.45) NPC1LMNAEPHX2ACHESMN1; SMN2
SCHEMBL28236249 0.91 NPC1 (0.45) NPC1LMNAEPHX2ACHESMN1; SMN2
SCHEMBL12200376 0.89 NPC1 (0.34) NPC1
SCHEMBL13652632 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108368016-B Process for producing cyclopentyl alkyl ether compound 日本瑞翁株式会社 2023-09-26 CN disclosed
US-20230250106-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2023-08-10 US disclosed
US-20230116972-A1 CD38 MODULATORS AND METHODS OF USE THEREOF CYTOKINETICS, INC. 2023-04-20 US disclosed
EP-3398928-B1 METHOD FOR PRODUCING CYCLOPENTYL ALKYL ETHER COMPOUND ZEON CORP (JP) 2021-01-20 EP disclosed
US-20180354880-A1 METHOD FOR PRODUCING CYCLOPENTYL ALKYL ETHER COMPOUND ZEON CORPORATION (JP) 2018-12-13 US disclosed
EP-3398928-A1 METHOD FOR PRODUCING CYCLOPENTYL ALKYL ETHER COMPOUND Zeon Corporation (JP) 2018-11-07 EP disclosed
CN-102898149-A Solvent or solvent composition for manufacturing laminated ceramic member DAICEL CHEM 2013-01-30 CN disclosed
US-20070265289-A1 2-Aminopyrimidine Derivative ASTELLAS PHARMA INC. (JP) 2007-11-15 US disclosed
US-20070265289-A1 2-Aminopyrimidine Derivative ASTELLAS PHARMA INC. (JP) 2007-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250106-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY STING1, CGAS, IRF3 NPC1 859/4885LMNA 2339/4885EPHX2 1579/4885
US-20230116972-A1 CD38 MODULATORS AND METHODS OF USE THEREOF CD38, CXCR4, FCGRT NPC1 2619/4885LMNA 1413/4885EPHX2 3254/4885
US-20070265289-A1 2-Aminopyrimidine Derivative NFKBIA, IKBKG, NFKB2 NPC1 4389/4885LMNA 4358/4885EPHX2 1504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.