Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL113242 | 0.82 | LMNA (1.00) | LMNATDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL14097078 | 0.79 | LMNA (0.68) | LMNATDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL11783550 | 0.79 | LMNA (0.68) | LMNATDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL27553727 | 0.79 | LMNA (0.68) | LMNATDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL18754429 | 0.79 | LMNA (0.68) | LMNATDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL26926832 | 0.79 | MAPK1 (0.49) | LMNAKDM4EALDH1A1POLBGAA | |
| SCHEMBL15636583 | 0.78 | LMNA (0.66) | LMNATDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL22932842 | 0.77 | LMNA (0.64) | LMNATDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL3091100 | 0.77 | LMNA (0.64) | LMNATDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL587516 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57067564-A | — | — | None | — | — | JP | disclosed |
| JP-S5767564-A | PRODUCTION OF 1,3-DIMETHYL-4-BENZOYL-5-HYDROXYPYRAZOLE | ISHIHARA SANGYO KAISHA LTD | 1982-04-24 | — | — | JP | disclosed |