SCHEMBL11228055

SCHEMBL11228055

CC(C)CC(C)C.N=C=O.N=C=O

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
RNPEP Q9H4A4 1/20 0.33
SLC7A5 Q01650 1/20 0.33
ANPEP P15144 4/20 0.32
LAP3 P28838 2/20 0.32
ERAP1 Q9NZ08 2/20 0.32
ERAP2 Q6P179 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11229664 0.84 CACNA2D1 (0.34) ALDH1A1TSHRMAPK1
SCHEMBL11222909 0.82 ALDH1A1 (0.30) ALDH1A1TSHRMAPK1
SCHEMBL28633153 0.80
SCHEMBL5696405 0.79 TSHR (0.33) TSHR
SCHEMBL7525622 0.79 CA1 (0.35) ALDH1A1
SCHEMBL834041 0.79
Isobutane SCHEMBL7910872 0.76
Isobutane SCHEMBL3986587 0.76
Isobutane SCHEMBL11409032 0.76
Isobutanol SCHEMBL9824220 0.76 TSHR (0.60) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4344891-A Halogenated tertiary alkyl isocyanates and their preparation BASF AKTIENGESELLSCHAFT (DE) 1982-08-17 US disclosed