Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641277 | 0.78 | TDP1 (0.56) | TDP1TSHRS1PR4MRGPRX4MAPT | |
| SCHEMBL11090538 | 0.75 | TDP1 (0.53) | TDP1TSHRS1PR4MAPTSMN1; SMN2 | |
| SCHEMBL11413525 | 0.74 | S1PR4 (0.66) | TDP1S1PR4MAPT | |
| SCHEMBL10379872 | 0.74 | TDP1 (0.60) | TDP1TSHRS1PR4MRGPRX4MAPT | |
| SCHEMBL11223887 | 0.74 | MAPT (0.55) | TDP1TSHRS1PR4MAPTSMN1; SMN2 | |
| SCHEMBL3275231 | 0.72 | TDP1 (0.58) | TDP1TSHRS1PR4MRGPRX4MAPT | |
| SCHEMBL96583 | 0.72 | MAPT (0.54) | TDP1TSHRS1PR4MAPTSMN1; SMN2 | |
| SCHEMBL8410383 | 0.72 | TDP1 (0.58) | TDP1TSHRS1PR4MAPTSMN1; SMN2 | |
| SCHEMBL3402920 | 0.71 | WDR5 (0.47) | SMN1; SMN2LMNAPOLBHTT | |
| SCHEMBL12360711 | 0.71 | TDP1 (0.56) | TDP1TSHRS1PR4MRGPRX4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046184-B1 | ARYLOXYALKYL ISOCYANATES AND METHODS FOR THEIR PREPARATION | BASF Aktiengesellschaft (DE) | 1983-11-23 | — | — | EP | disclosed |
| EP-0046184-A1 | Aryloxyalkyl isocyanates and methods for their preparation | BASF Aktiengesellschaft (DE) | 1982-02-24 | — | — | EP | disclosed |