Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 12/20 | 1.00 |
| ▸ | AKR1C1 | Q04828 | 12/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.66 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.64 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.62 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.55 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.55 |
| ▸ | HNF4A | P41235 | 2/20 | 0.55 |
| ▸ | DHFR | P00374 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27999624 | 0.86 | PTPN1 (0.78) | AKR1C2AKR1C1PTPN1AKR1C4AKR1C3 | |
| SCHEMBL6850839 | 0.83 | AKR1C2 (0.71) | AKR1C2AKR1C1PTPN1AKR1C4AKR1C3 | |
| SCHEMBL3564211 | 0.82 | TTR (0.70) | AKR1C2AKR1C1ALDH1A1HSD17B10FTO | |
| SCHEMBL4833538 | 0.80 | AKR1C2 (0.74) | AKR1C2AKR1C1PTPN1AKR1C4AKR1C3 | |
| SCHEMBL18304655 | 0.80 | AKR1C2 (0.67) | AKR1C2AKR1C1PTPN1AKR1C4AKR1C3 | |
| SCHEMBL11693280 | 0.80 | AKR1C2 (0.66) | AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL5437754 | 0.79 | PTPN1 (1.00) | AKR1C2AKR1C1PTPN1AKR1C4AKR1C3 | |
| SCHEMBL18319714 | 0.78 | AKR1C2 (1.00) | AKR1C2AKR1C1PTPN1AKR1C4AKR1C3 | |
| SCHEMBL6055013 | 0.78 | AKR1C2 (1.00) | AKR1C2AKR1C1PTPN1AKR1C4AKR1C3 | |
| SCHEMBL8046560 | 0.78 | PTPN1 (0.66) | AKR1C2AKR1C1PTPN1AKR1C4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10702537-B2 | Devices and methods of treating methamphetamine addiction and medical and behavioral consequences of methamphetamine use and of HIV infection | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2020-07-07 | — | — | US | disclosed |
| US-10561668-B1 | Devices and methods of treating methamphetamine addiction and medical and behavioral consequences of methamphetamine use and of HIV infection | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (US) | 2020-02-18 | — | — | US | disclosed |
| US-20190224211-A1 | DEVICES AND METHODS OF TREATING METHAMPHETAMINE ADDICTION AND MEDICAL AND BEHAVIORAL CONSEQUENCES OF METHAMPHETAMINE USE AND OF HIV INFECTION | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2019-07-25 | — | — | US | disclosed |
| US-10022383-B2 | Devices and methods of treating methamphetamine addiction and medical and behavioral consequences of methamphetamine use and of HIV infection | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2018-07-17 | — | — | US | disclosed |
| US-20160367565-A1 | DEVICES AND METHODS OF TREATING METHAMPHETAMINE ADDICTION AND MEDICAL AND BEHAVIORAL CONSEQUENCES OF METHAMPHETAMINE USE AND OF HIV INFECTION | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2016-12-22 | — | — | US | disclosed |
| US-4355070-A | COLOR FORMER, DEVELOPER, HEAT FUSIBLE MATERIAL AND OIL ABSORPTIVE PIGMENT | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1982-10-19 | — | — | US | disclosed |
| US-4311758-A | INORGANIC PIGMENTS IN THE COLOR DEVELOPER LAYER | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1982-01-19 | — | — | US | disclosed |
| US-4236732-A | COLOR DEVELOPING LAYER CONTAINING PARTICLES OF A CHROMOGENIC MATERIAL, AN ACCEPTOR AND A HEAT FUSIBLE MATERIAL | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1980-12-02 | — | — | US | disclosed |
| US-4228222-A | COLOR DEVELOPING LAYER INCLUDING WATER SOLUBLE RESIN AS BINDER | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1980-10-14 | — | — | US | disclosed |
| US-4168845-A | Heat-sensitive record material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1979-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10022383-B2 | Devices and methods of treating methamphetamine addiction and medical and behavioral consequences of methamphetamine use and of HIV infection | TSPO, SLC18A2, SLC18A3 | AKR1C2 3197/4885AKR1C1 3135/4885PTPN1 4622/4885 |
| US-10561668-B1 | Devices and methods of treating methamphetamine addiction and medical and behavioral consequences of methamphetamine use and of HIV infection | TSPO, SLC18A2, SLC18A3 | AKR1C2 3197/4885AKR1C1 3135/4885PTPN1 4622/4885 |
| US-20160367565-A1 | DEVICES AND METHODS OF TREATING METHAMPHETAMINE ADDICTION AND MEDICAL AND BEHAVIORAL CONSEQUENCES OF METHAMPHETAMINE USE AND OF HIV INFECTION | TSPO, SLC18A2, SLC18A3 | AKR1C2 3197/4885AKR1C1 3135/4885PTPN1 4622/4885 |
| US-10702537-B2 | Devices and methods of treating methamphetamine addiction and medical and behavioral consequences of methamphetamine use and of HIV infection | TSPO, SLC18A2, SLC18A3 | AKR1C2 3197/4885AKR1C1 3135/4885PTPN1 4622/4885 |
| US-20190224211-A1 | DEVICES AND METHODS OF TREATING METHAMPHETAMINE ADDICTION AND MEDICAL AND BEHAVIORAL CONSEQUENCES OF METHAMPHETAMINE USE AND OF HIV INFECTION | TSPO, SLC18A2, SLC18A3 | AKR1C2 3197/4885AKR1C1 3135/4885PTPN1 4622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.