SCHEMBL11228231

SCHEMBL11228231

CC(=CCCC(=O)CCl)CCC(=O)O

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FNTA P49354 6/20 0.54
FNTB P49356 6/20 0.54
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
TRPA1 O75762 1/20 0.41
MAPT P10636 1/20 0.41
IMPDH2 P12268 4/20 0.40
LMNA P02545 1/20 0.38
SLC15A2 Q16348 1/20 0.38
ALDH1A1 P00352 1/20 0.38
ALOX15 P16050 1/20 0.38
KDM4E B2RXH2 2/20 0.38
KDM6B O15054 1/20 0.38
KDM5C P41229 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
PHF8 Q9UPP1 1/20 0.38
KDM2A Q9Y2K7 1/20 0.38
ATM Q13315 1/20 0.37
FAAH O00519 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11228228 1.00 FNTA (0.54) FNTAFNTBKMT2AMEN1TRPA1
SCHEMBL8927123 0.83 FNTA (0.55) FNTAFNTBKMT2AMEN1TRPA1
SCHEMBL12591519 0.82 KMT2A (0.61) FNTAFNTBKMT2AMEN1TRPA1
SCHEMBL9515236 0.82 KMT2A (0.61) FNTAFNTBKMT2AMEN1TRPA1
SCHEMBL10501700 0.82 KMT2A (0.61) FNTAFNTBKMT2AMEN1TRPA1
SCHEMBL10885753 0.81 FNTA (0.54) FNTAFNTBKMT2AMEN1TRPA1
SCHEMBL11765631 0.79 FNTA (0.47) FNTAFNTBKMT2AMEN1TRPA1
SCHEMBL11765636 0.79 FNTA (0.47) FNTAFNTBKMT2AMEN1TRPA1
SCHEMBL22555394 0.78 FNTA (0.55) FNTAFNTBKMT2AMEN1TRPA1
SCHEMBL22555392 0.78 FNTA (0.55) FNTAFNTBKMT2AMEN1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57183774-A None JP disclosed
JP-S57183774-A TETRAHYDROFURAN COMPOUND AND ITS PREPARATION MITSUBISHI CHEM IND LTD 1982-11-12 JP disclosed