SCHEMBL10501700

SCHEMBL10501700

CC(C)=CCCC(C)=CCCC(C)=CCCC(=O)CCl

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.61
FNTA P49354 4/20 0.61
FNTB P49356 4/20 0.61
ALOX15 P16050 3/20 0.56
ALDH1A1 P00352 2/20 0.56
MAPT P10636 3/20 0.55
MEN1 O00255 3/20 0.55
CYP3A4 P08684 2/20 0.55
UGT1A1 P22309 1/20 0.55
SQLE Q14534 1/20 0.53
KDM4E B2RXH2 2/20 0.52
ATM Q13315 1/20 0.52
POLB P06746 1/20 0.50
TRPA1 O75762 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9515236 1.00 KMT2A (0.61) KMT2AFNTAFNTBALOX15ALDH1A1
SCHEMBL12591519 1.00 KMT2A (0.61) KMT2AFNTAFNTBALOX15ALDH1A1
SCHEMBL15639481 0.87 FNTA (0.75) KMT2AFNTAFNTBALOX15ALDH1A1
SCHEMBL4783049 0.87 FNTA (0.75) KMT2AFNTAFNTBALOX15ALDH1A1
SCHEMBL7884676 0.85 FNTA (0.72) KMT2AFNTAFNTBALOX15ALDH1A1
SCHEMBL7773863 0.84 ICMT (0.62) KMT2AFNTAFNTBALOX15ALDH1A1
SCHEMBL11228228 0.82 FNTA (0.54) KMT2AFNTAFNTBALOX15ALDH1A1
SCHEMBL11228231 0.82 FNTA (0.54) KMT2AFNTAFNTBALOX15ALDH1A1
SCHEMBL726070 0.82 KMT2A (0.64) KMT2AFNTAFNTBALOX15ALDH1A1
SCHEMBL10036544 0.82 KMT2A (0.64) KMT2AFNTAFNTBALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0145554-B1 PROCESS FOR THE PREPARATION OF CHLORINATED ETHYLENIC COMPOUNDS RHONE-POULENC SANTE (FR) 1989-01-25 EP disclosed
EP-0145554-A2 Process for the preparation of chlorinated ethylenic compounds RHONE-POULENC SANTE (FR) 1985-06-19 EP disclosed