Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | BAX | Q07812 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278018 | 0.84 | PTGS1 (0.50) | PTGS1MEN1CYP2D6KMT2AAKR1C3 | |
| SCHEMBL10703179 | 0.84 | PTGS1 (0.54) | PTGS1MEN1CYP2D6KMT2AAKR1C3 | |
| SCHEMBL10784527 | 0.83 | PTGS1 (0.49) | PTGS1MEN1CYP2D6KMT2AAKR1C3 | |
| SCHEMBL29890128 | 0.80 | TSHR (0.60) | PTGS1MEN1CYP2D6KMT2AAKR1C3 | |
| SCHEMBL10550089 | 0.80 | PTGS1 (0.57) | PTGS1MEN1CYP2D6KMT2AAKR1C3 | |
| SCHEMBL10686594 | 0.80 | PTGS1 (0.57) | PTGS1MEN1CYP2D6KMT2AAKR1C3 | |
| SCHEMBL1677135 | 0.80 | TSHR (0.60) | PTGS1MEN1CYP2D6KMT2AAKR1C3 | |
| SCHEMBL30045078 | 0.80 | TSHR (0.60) | PTGS1MEN1CYP2D6KMT2AAKR1C3 | |
| SCHEMBL8577668 | 0.80 | PTGS1 (0.57) | PTGS1MEN1CYP2D6KMT2AAKR1C3 | |
| SCHEMBL192456 | 0.80 | TSHR (0.60) | PTGS1MEN1CYP2D6KMT2AAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349567-A | Dihalovinylcyclopropanecarboxylic acid esters and their use in pest control | CIBA-GEIGY CORPORATION (US) | 1982-09-14 | — | — | US | disclosed |
| US-4331682-A | Cyclopropanecarboxylic acid-α-haloethynyl-m-phenoxybenzyl esters and their use for combating insect pests | CIBA-GEIGY CORPORATION (US) | 1982-05-25 | — | — | US | disclosed |