Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.67 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29006844 | 0.80 | CYP19A1 (0.67) | CYP19A1CYP3A4CYP2C19CYP11B1TSHR | |
| SCHEMBL13292485 | 0.80 | CYP19A1 (1.00) | CYP19A1CYP26A1CYP3A4CYP2C19CYP11B1 | |
| SCHEMBL28868949 | 0.78 | CYP19A1 (0.69) | CYP19A1CYP26A1CYP2D6MEN1KMT2A | |
| SCHEMBL9158120 | 0.78 | CYP19A1 (0.71) | CYP19A1CYP3A4CYP2C19CYP11B1TSHR | |
| SCHEMBL28270627 | 0.77 | CYP19A1 (0.67) | CYP19A1CYP26A1CYP2D6MEN1KMT2A | |
| SCHEMBL27689440 | 0.77 | CYP19A1 (0.67) | CYP19A1CYP26A1CYP2D6MEN1KMT2A | |
| SCHEMBL31186033 | 0.75 | NPC1 (0.48) | CYP19A1CYP26A1MEN1KMT2AMAPT | |
| SCHEMBL11563115 | 0.75 | CYP19A1 (0.50) | CYP19A1CYP26A1CYP2D6MEN1KMT2A | |
| SCHEMBL31185779 | 0.74 | CYP19A1 (0.53) | CYP19A1KMT2ACYP3A4CYP2C19HSP90AA1 | |
| SCHEMBL9795396 | 0.74 | CYP19A1 (0.49) | CYP19A1CYP26A1CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315017-A | Triazole derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-09 | — | — | US | disclosed |
| EP-0008651-B1 | DERIVATIVES OF TRIAZOLE, PROCESS FOR THEIR PRODUCTION AND INSECTICIDES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1981-10-14 | — | — | EP | disclosed |
| EP-0008651-A1 | Derivatives of triazole, process for their production and insecticides containing them | BASF Aktiengesellschaft (DE) | 1980-03-19 | — | — | EP | disclosed |