Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | PARP1 | P09874 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 8/20 | 0.54 |
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | PKM | P14618 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.54 |
| ▸ | RELA | Q04206 | 2/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | STAT1 | P42224 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221748 | 0.86 | PARP1 (0.67) | TSHRPARP1LMNANPC1RAB9A | |
| SCHEMBL24026375 | 0.81 | PARP1 (0.67) | TSHRPARP1LMNANPC1RAB9A | |
| SCHEMBL1781609 | 0.81 | ALDH1A1 (0.56) | TSHRPARP1LMNANPC1RAB9A | |
| SCHEMBL659214 | 0.79 | TSHR (0.71) | TSHRPARP1LMNANPC1RAB9A | |
| SCHEMBL13278295 | 0.77 | TSHR (0.64) | TSHRPARP1LMNANPC1RAB9A | |
| SCHEMBL11924524 | 0.76 | TSHR (0.63) | TSHRPARP1LMNANPC1RAB9A | |
| SCHEMBL13035816 | 0.75 | TSHR (0.67) | TSHRPARP1LMNANPC1RAB9A | |
| SCHEMBL7955024 | 0.75 | TSHR (0.67) | TSHRPARP1LMNANPC1RAB9A | |
| SCHEMBL9891915 | 0.75 | TSHR (0.66) | TSHRPARP1LMNANPC1RAB9A | |
| SCHEMBL12922693 | 0.75 | PARP1 (0.53) | TSHRPARP1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4319914-A | POSTEMERGENCE HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1982-03-16 | — | — | US | disclosed |