Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15274399 | 0.79 | KMT2A (0.66) | SMN1; SMN2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL2171105 | 0.78 | SMN1; SMN2 (0.66) | SMN1; SMN2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL1747979 | 0.74 | SMN1; SMN2 (0.61) | SMN1; SMN2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL30944287 | 0.74 | SMN1; SMN2 (1.00) | SMN1; SMN2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL10991202 | 0.74 | SMN1; SMN2 (1.00) | SMN1; SMN2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL4819924 | 0.74 | RAPGEF4 (0.53) | SMN1; SMN2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL11848824 | 0.73 | NPC1 (0.44) | SMN1; SMN2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL30862384 | 0.73 | NPC1 (0.44) | SMN1; SMN2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL26458871 | 0.73 | NPC1 (1.00) | SMN1; SMN2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL11850147 | 0.72 | DYRK1A (0.64) | SMN1; SMN2KMT2ANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57067566-A | — | — | None | — | — | JP | disclosed |
| JP-S5767566-A | PRODUCTION OF BENZOTHIAZOLE DERIVATIVE | NIPPON SODA CO LTD | 1982-04-24 | — | — | JP | disclosed |