Chlorobenzilate

Chlorobenzilate

SCHEMBL11228679

CCOC(=O)C(O)(c1ccc(Cl)cc1)c1ccc(Cl)cc1.Clc1ccc(C(c2ccc(Cl)cc2)C(Cl)(Cl)Cl)cc1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
TSHR P16473 4/20 0.49
TDP1 Q9NUW8 4/20 0.49
LMNA P02545 3/20 0.49
HIF1A Q16665 2/20 0.49
MAPK1 P28482 2/20 0.49
TP53 P04637 1/20 0.49
HPGD P15428 1/20 0.49
ABCB11 O95342 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
HTR2A P28223 1/20 0.46
PMP22 Q01453 1/20 0.46
PPARA Q07869 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.42
HTT P42858 1/20 0.42
OPRK1 P41145 1/20 0.40
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzilate SCHEMBL28048828 0.87 MEN1 (0.60) MEN1KMT2ATSHRTDP1HPGD
Chlorobenzilate SCHEMBL73255 0.87 MEN1 (0.60) MEN1KMT2ATSHRTDP1HPGD
SCHEMBL27347358 0.81 MEN1 (0.54) MEN1KMT2ATSHRABCB11CYP1A2
Chlorobenzilate SCHEMBL6243435 0.81 MEN1 (0.54) MEN1KMT2ATSHRABCB11CYP1A2
SCHEMBL6812442 0.76 TSHR (0.59) MEN1KMT2ATSHRTDP1LMNA
Chlorobenzilate SCHEMBL29993079 0.76 KMT2A (0.48) MEN1KMT2ATSHRLMNATP53
SCHEMBL27362956 0.75 MEN1 (0.57) MEN1KMT2ATSHRLMNAABCB11
SCHEMBL10817757 0.75 TSHR (0.57) MEN1KMT2ATSHRTDP1MAPK1
SCHEMBL8652911 0.75 ABCB11 (0.57) MEN1KMT2ATSHRTDP1MAPK1
Chlorophenothane SCHEMBL28155106 0.74 TSHR (0.75) MEN1KMT2ATSHRTDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4323578-A Fluorinated carbamate insecticides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-04-06 US disclosed