Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.73 |
| ▸ | MAOB | P27338 | 1/20 | 0.73 |
| ▸ | GRM2 | Q14416 | 10/20 | 0.67 |
| ▸ | CALML3 | P27482 | 6/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11554348 | 0.86 | MAOA (0.73) | MAOAMAOBGRM2CALML3 | |
| SCHEMBL1557298 | 0.84 | MAOA (0.71) | MAOAMAOBGRM2CALML3 | |
| SCHEMBL30063909 | 0.84 | MAOA (0.71) | MAOAMAOBGRM2CALML3 | |
| SCHEMBL1032517 | 0.84 | MAOA (0.71) | MAOAMAOBGRM2CALML3 | |
| Toloxatone SCHEMBL29394786 | 0.84 | MAOA (1.00) | MAOAMAOBGRM2CALML3 | |
| SCHEMBL24731394 | 0.84 | MAOA (0.71) | MAOAMAOBGRM2CALML3 | |
| SCHEMBL3087781 | 0.84 | MAOA (0.71) | MAOAMAOBGRM2CALML3 | |
| Toloxatone SCHEMBL49437 | 0.84 | MAOA (1.00) | MAOAMAOBGRM2CALML3 | |
| SCHEMBL1874998 | 0.83 | GRM2 (0.69) | MAOAMAOBGRM2 | |
| SCHEMBL4638737 | 0.83 | GRM2 (0.69) | MAOAMAOBGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338451-A | ANTIDEPRESSANTS | DELALANDE S.A. (FR) | 1982-07-06 | — | — | US | disclosed |
| US-4250318-A | ANTIDEPRESSANTS | DELALANDE S.A. (FR) | 1981-02-10 | — | — | US | disclosed |