Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | TDO2 | P48775 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobenzene SCHEMBL6243441 | 0.83 | CYP1A2 (0.45) | TSHRALDH1A1PPARGCYP1A2MEN1 | |
| Dicofol SCHEMBL9456194 | 0.79 | TSHR (0.55) | TSHRMAPK1LMNAHIF1APPARG | |
| SCHEMBL73257 | 0.79 | CYP1A2 (0.52) | TSHRMAPK1HIF1AALDH1A1CYP1A2 | |
| SCHEMBL11032766 | 0.74 | CYP3A4 (0.42) | TSHRLMNAPPARGCYP1A2MEN1 | |
| Chlorophenothane SCHEMBL11228694 | 0.74 | TSHR (0.49) | TSHRMAPK1TDP1LMNATP53 | |
| SCHEMBL11613900 | 0.72 | TSHR (0.42) | TSHRMAPK1TDP1LMNATP53 | |
| Chlorophenothane SCHEMBL7181 | 0.72 | TSHR (1.00) | TSHRMAPK1TDP1LMNATP53 | |
| Chlorophenothane SCHEMBL2065589 | 0.72 | TSHR (1.00) | TSHRMAPK1TDP1LMNATP53 | |
| SCHEMBL9291597 | 0.70 | MEN1 (0.43) | LMNAPPARGCYP1A2MEN1KMT2A | |
| Chlorophenothane SCHEMBL28353116 | 0.70 | TSHR (0.86) | TSHRMAPK1TDP1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323578-A | Fluorinated carbamate insecticides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-04-06 | — | — | US | disclosed |