Chlorophenothane

Chlorophenothane

SCHEMBL2065589

Clc1ccc(C(c2ccc(Cl)cc2)C(Cl)(Cl)Cl)cc1.Clc1ccc(C(c2ccc(Cl)cc2)C(Cl)(Cl)Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 1.00
MAPK1 P28482 4/20 1.00
TDP1 Q9NUW8 3/20 1.00
HIF1A Q16665 3/20 1.00
LMNA P02545 2/20 1.00
TP53 P04637 1/20 1.00
HPGD P15428 1/20 1.00
ALDH1A1 P00352 2/20 0.63
ESR1 P03372 1/20 0.61
ESR2 Q92731 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.54
CYP2A6 P11509 1/20 0.44
ADRB2 P07550 1/20 0.44
CYP19A1 P11511 3/20 0.41
IDO1 P14902 2/20 0.41
TDO2 P48775 2/20 0.41
AHR P35869 1/20 0.39
CYP1A2 P05177 1/20 0.38
BRD4 O60885 1/20 0.37
HDAC4 P56524 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorophenothane SCHEMBL7181 1.00 TSHR (1.00) TSHRMAPK1TDP1HIF1ALMNA
Chlorophenothane SCHEMBL3798614 0.97 TSHR (0.95) TSHRMAPK1TDP1HIF1ALMNA
Chlorophenothane SCHEMBL9765829 0.97 TSHR (0.95) TSHRMAPK1TDP1HIF1ALMNA
Chlorophenothane SCHEMBL7765752 0.97 TSHR (0.95) TSHRMAPK1TDP1HIF1ALMNA
Chlorophenothane SCHEMBL891471 0.97 TSHR (0.95) TSHRMAPK1TDP1HIF1ALMNA
Chlorophenothane SCHEMBL10725072 0.97 TSHR (0.95) TSHRMAPK1TDP1HIF1ALMNA
Chlorophenothane SCHEMBL8508193 0.95 TSHR (0.90) TSHRMAPK1TDP1HIF1ALMNA
Chlorophenothane SCHEMBL28353116 0.93 TSHR (0.86) TSHRMAPK1TDP1HIF1ALMNA
Chlorophenothane SCHEMBL11570317 0.93 TSHR (0.86) TSHRMAPK1TDP1HIF1ALMNA
Chlorophenothane SCHEMBL30308710 0.91 TSHR (0.82) TSHRMAPK1TDP1HIF1ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102409027-A Enzyme linked immunosorbent assay kit for rapidly detecting dichlorodiphenyl trichloroethane and metabolites thereof and preparation method thereof NAT MARINE ENVIRONMENTAL MONITORING CT 2012-04-11 CN claimed
EP-3688472-A1 CONJUGATED PROTEINS AND USES THEREOF The Scripps Research Institute (US) 2020-08-05 EP disclosed
WO-2019067741-A1 CONJUGATED PROTEINS AND USES THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2019-04-04 WO disclosed
CN-103301887-A Catalyst for treating chorine-containing organic matters in water and preparation method thereof CHEN HEPING 2013-09-18 CN disclosed
CN-101978892-B Bamboo vinegar anti-alcoholic beverage and preparation method thereof ZHIYONG WANG 2012-08-15 CN disclosed
CN-101972025-B Bamboo vinegar health care beverage and preparation method thereof ZHIYONG WANG 2012-07-25 CN disclosed
CN-102409027-A Enzyme linked immunosorbent assay kit for rapidly detecting dichlorodiphenyl trichloroethane and metabolites thereof and preparation method thereof NAT MARINE ENVIRONMENTAL MONITORING CT 2012-04-11 CN disclosed
US-8150040-B2 Key providing system, terminal device, and information processing method SONY CORPORATION (JP) 2012-04-03 US disclosed
CN-101978892-A Bamboo vinegar anti-alcoholic beverage and preparation method thereof ZHIYONG WANG 2011-02-23 CN disclosed
CN-101972025-A Bamboo vinegar health care beverage and preparation method thereof ZHIYONG WANG 2011-02-16 CN disclosed
US-5976770-A Dyed photoresists and methods and articles of manufacture comprising same SHIPLEY COMPANY, L.L.C. (US) 1999-11-02 US disclosed
EP-0749468-B1 REFINING OIL COMPOSITIONS NORSK HYDRO AS (NO) 1999-05-19 EP disclosed
US-5858713-A ISOLATED MUTANT NUCLEIC ACIDS FROM DROSOPHILA MELANOGASTER, MUSCA DOMESTICA, AND HELIOTHIS VIRESCENS FOR SCREENING INSECTICIDES CORNELL RESEARCH FOUNDATION, INC. (US) 1999-01-12 US disclosed
EP-0768824-A4 INSECT CONTROL METHOD WITH GENETICALLY ENGINEERED BIOPESTICIDES UNIV CALIFORNIA (US) 1998-12-09 EP disclosed
EP-0768824-A1 INSECT CONTROL METHOD WITH GENETICALLY ENGINEERED BIOPESTICIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1997-04-23 EP disclosed
EP-0749468-A1 REFINING OIL COMPOSITIONS NORSK HYDRO a.s. (NO) 1996-12-27 EP disclosed
WO-1996001055-A1 INSECT CONTROL METHOD WITH GENETICALLY ENGINEERED BIOPESTICIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-01-18 WO disclosed
WO-1995024459-A1 REFINING OIL COMPOSITIONS NORSK HYDRO A.S (NO) 1995-09-14 WO disclosed
EP-0192237-B1 PROCESS FOR THE DEGRADATION OF ENVIROMENTALLY PERSISTENT ORGANIC COMPOUNDS Utah State University Foundation (US) 1990-06-27 EP disclosed
US-3939277-A 1-(P-ALKOXYPHENYL)-1-(P-METHYLPHENYL-2,2,2-TRICHLORO-ETHANE THE UNIVERSITY OF ILLINOIS FOUNDATION (US) 1976-02-17 US disclosed