Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1L1 | Q9UHC9 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.39 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14001699 | 1.00 | NPC1L1 (0.42) | NPC1L1MEN1LMNAKMT2AUSP2 | |
| SCHEMBL26669398 | 0.90 | NPC1L1 (0.39) | NPC1L1MEN1LMNAKMT2AUSP2 | |
| SCHEMBL22646215 | 0.89 | RORC (0.48) | NPC1L1MEN1LMNAKMT2AUSP2 | |
| SCHEMBL12947553 | 0.89 | RORC (0.48) | NPC1L1MEN1LMNAKMT2AUSP2 | |
| SCHEMBL12917608 | 0.89 | RORC (0.48) | NPC1L1MEN1LMNAKMT2AUSP2 | |
| SCHEMBL967993 | 0.89 | RORC (0.48) | NPC1L1MEN1LMNAKMT2AUSP2 | |
| SCHEMBL11823290 | 0.89 | RORC (0.48) | NPC1L1MEN1LMNAKMT2AUSP2 | |
| SCHEMBL9827579 | 0.88 | NPC1L1 (0.45) | NPC1L1MEN1LMNAKMT2AUSP2 | |
| SCHEMBL9829186 | 0.87 | GPBAR1 (0.47) | NPC1L1MEN1LMNAKMT2AUSP2 | |
| SCHEMBL26669399 | 0.87 | GPBAR1 (0.47) | NPC1L1MEN1LMNAKMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4354972-A | Synthesis of steroids | KAISER EMIL T | 1982-10-19 | — | — | US | disclosed |