Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11228791 | 1.00 | TDP1 (0.58) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL29365125 | 0.90 | TDP1 (0.70) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL49899 | 0.90 | TDP1 (0.70) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL9447258 | 0.86 | TDP1 (0.59) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL13719391 | 0.80 | CYP3A4 (0.57) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL8746590 | 0.80 | TDP1 (0.56) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL333218 | 0.79 | CYP3A4 (0.61) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL333217 | 0.79 | CYP3A4 (0.61) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL11748612 | 0.77 | MAPK1 (0.53) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL8673120 | 0.77 | MAPK1 (0.53) | TDP1MAPK1CYP3A4TRPA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318850-A | Carboxamide type azomethine pigment | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1982-03-09 | — | — | US | disclosed |