Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.32 |
| ▸ | SENP3 | Q9H4L4 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49899 | 0.88 | TDP1 (0.70) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL29365125 | 0.88 | TDP1 (0.70) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL9447258 | 0.83 | TDP1 (0.59) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL1969589 | 0.83 | CYP1A2 (0.52) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL11228792 | 0.80 | TDP1 (0.58) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL11228791 | 0.80 | TDP1 (0.58) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| Toluene SCHEMBL11667802 | 0.79 | CYP3A4 (0.51) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL27066 | 0.78 | CYP3A4 (0.50) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL29405309 | 0.78 | CYP3A4 (0.50) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL13719391 | 0.77 | CYP3A4 (0.57) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406702-B1 | Preparation of polyurethane foams without using inert blowing agents | UNION CARBIDE CHEM PLASTIC (US) | 1997-03-05 | — | — | EP | disclosed |
| EP-0492464-A2 | Reactive feed stream to replace inert blowing agent feed stream in a polyurethane foam process | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) | 1992-07-01 | — | — | EP | disclosed |
| US-5084486-A | Polymerization and blowing followed by molding | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1992-01-28 | — | — | US | disclosed |
| EP-0406702-A1 | Preparation of polyurethane foams without using inert blowing agents | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) | 1991-01-09 | — | — | EP | disclosed |
| US-4950694-A | Preparation of polyurethane foams without using inert blowing agents | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) | 1990-08-21 | — | — | US | disclosed |