Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL189727 | 0.87 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3LMNACYP2D6 | |
| SCHEMBL28579 | 0.87 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3LMNACYP2D6 | |
| Benzene SCHEMBL28876392 | 0.87 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3LMNACYP2D6 | |
| SCHEMBL420409 | 0.87 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3LMNACYP2D6 | |
| SCHEMBL28190929 | 0.87 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3LMNACYP2D6 | |
| SCHEMBL11680566 | 0.87 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3LMNACYP2D6 | |
| Diphenylmethane SCHEMBL333766 | 0.87 | CALM1 (0.67) | CALM1PTPN1PLA2G10PLA2G2ALMNA | |
| Diphenylmethane SCHEMBL465158 | 0.87 | CALM1 (0.67) | CALM1PTPN1PLA2G10PLA2G2ALMNA | |
| Diphenylmethane SCHEMBL9449990 | 0.87 | CALM1 (0.67) | CALM1PTPN1PLA2G10PLA2G2ALMNA | |
| Diphenylmethane SCHEMBL15415 | 0.87 | CALM1 (0.67) | CALM1PTPN1PLA2G10PLA2G2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4351873-A | OF A CLOSED-CELL FOAM CONTAINING A FLUOROCARBON GAS | GAF CORPORATION (US) | 1982-09-28 | — | — | US | disclosed |