Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9381581 | 0.90 | TSHR (0.64) | TSHRHSP90AA1RAB9ACYP3A4CA12 | |
| SCHEMBL30543010 | 0.85 | TERT (0.53) | TSHRTERTALDH1A1LMNAADAMTS5 | |
| SCHEMBL30358272 | 0.85 | CYP3A4 (0.58) | TSHRHSP90AA1CYP3A4CA12ALDH1A1 | |
| SCHEMBL813557 | 0.85 | CYP3A4 (0.58) | TSHRHSP90AA1CYP3A4CA12ALDH1A1 | |
| SCHEMBL1277058 | 0.84 | TSHR (0.50) | TSHRHSP90AA1RAB9ACYP3A4ALDH1A1 | |
| SCHEMBL30628468 | 0.84 | TSHR (0.50) | TSHRHSP90AA1RAB9ACYP3A4ALDH1A1 | |
| SCHEMBL29719326 | 0.83 | CYP3A4 (0.55) | TSHRCYP3A4CA12ALDH1A1CA2 | |
| SCHEMBL3182473 | 0.83 | CYP3A4 (0.55) | TSHRCYP3A4CA12ALDH1A1CA2 | |
| SCHEMBL5143789 | 0.83 | CYP3A4 (0.55) | TSHRCYP3A4CA12ALDH1A1CA2 | |
| SCHEMBL18179763 | 0.82 | HSP90AA1 (0.56) | TSHRHSP90AA1RAB9ACYP3A4STK39 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339462-A | BACTERICIDES | CIBA-GEIGY CORPORATION (US) | 1982-07-13 | — | — | US | disclosed |
| US-4268693-A | 3-Hydroxydiphenyl ethers | CIBA-GEIGY CORPORATION (US) | 1981-05-19 | — | — | US | disclosed |