Naphthoquinone

Naphthoquinone

SCHEMBL11229112

O=C1C=CC(=O)c2ccccc21.[Ni]

nearest known ligand 0.93

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 6/20 0.93
CDC25B P30305 5/20 0.93
MAOA P21397 4/20 0.93
MAOB P27338 3/20 0.93
PIN1 Q13526 2/20 0.93
EHMT2 Q96KQ7 2/20 0.93
SNCA P37840 2/20 0.93
AKT1 P31749 1/20 0.93
MAP2K1 Q02750 1/20 0.93
NSD1 Q96L73 1/20 0.93
EHMT1 Q9H9B1 1/20 0.93
MEN1 O00255 7/20 0.52
KMT2A Q03164 7/20 0.52
ALDH1A1 P00352 6/20 0.52
MAPT P10636 5/20 0.52
HPGD P15428 5/20 0.52
RECQL P46063 4/20 0.52
KDM4E B2RXH2 4/20 0.52
ALOX15 P16050 4/20 0.52
LMNA P02545 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthoquinone SCHEMBL29354680 0.97 IDO1 (1.00) IDO1CDC25BMAOAMAOBPIN1
Naphthoquinone SCHEMBL42139 0.97 IDO1 (1.00) IDO1CDC25BMAOAMAOBPIN1
Naphthoquinone SCHEMBL11359780 0.97 IDO1 (1.00) IDO1CDC25BMAOAMAOBPIN1
Naphthoquinone SCHEMBL8861335 0.97 IDO1 (1.00) IDO1CDC25BMAOAMAOBPIN1
Naphthoquinone SCHEMBL14763779 0.93 IDO1 (0.93) IDO1CDC25BMAOAMAOBPIN1
Naphthoquinone SCHEMBL5049300 0.93 IDO1 (0.93) IDO1CDC25BMAOAMAOBPIN1
Naphthoquinone SCHEMBL2208241 0.93 CDC25B (0.93) IDO1CDC25BMAOAMAOBPIN1
Naphthoquinone SCHEMBL10908172 0.93 IDO1 (0.93) IDO1CDC25BMAOAMAOBPIN1
Naphthoquinone SCHEMBL2722901 0.93 IDO1 (0.93) IDO1CDC25BMAOAMAOBPIN1
Naphthoquinone SCHEMBL722080 0.93 IDO1 (0.93) IDO1CDC25BMAOAMAOBPIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109467625-A Aniline oximes catalyst and preparation method thereof 东华大学 2019-03-15 CN disclosed
US-4317748-A Process for the preparation of supported nickel catalysts EMERY INDUSTRIES, INC. (US) 1982-03-02 US disclosed