Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1388254 | 1.00 | TSHR (0.46) | TSHRALDH1A1FAAHTRPV1F7 | |
| SCHEMBL8959959 | 1.00 | TSHR (0.46) | TSHRALDH1A1FAAHTRPV1F7 | |
| SCHEMBL9802043 | 1.00 | TSHR (0.46) | TSHRALDH1A1FAAHTRPV1F7 | |
| SCHEMBL9801187 | 1.00 | TSHR (0.46) | TSHRALDH1A1FAAHTRPV1F7 | |
| SCHEMBL995957 | 0.97 | TSHR (0.46) | TSHRALDH1A1FAAHTRPV1F7 | |
| SCHEMBL9801479 | 0.95 | TSHR (0.52) | TSHRALDH1A1FAAHTRPV1THRB | |
| SCHEMBL9801443 | 0.95 | TSHR (0.52) | TSHRALDH1A1FAAHTRPV1THRB | |
| SCHEMBL235185 | 0.95 | TSHR (0.52) | TSHRALDH1A1FAAHTRPV1THRB | |
| SCHEMBL9801641 | 0.95 | TSHR (0.52) | TSHRALDH1A1FAAHTRPV1THRB | |
| SCHEMBL2945293 | 0.95 | TSHR (0.52) | TSHRALDH1A1FAAHTRPV1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4330606-A | ANTIFADING AGENT | AGFA-GEVAERT AG (DE) | 1982-05-18 | — | — | US | disclosed |