SCHEMBL995957

SCHEMBL995957

[CH2]CCCC[CH]CCCC

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.46
ALDH1A1 P00352 2/20 0.46
F7 P08709 1/20 0.32
F3 P13726 1/20 0.32
FAAH O00519 2/20 0.32
TRPV1 Q8NER1 1/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1388254 0.97 TSHR (0.46) TSHRALDH1A1F7F3FAAH
SCHEMBL9802043 0.97 TSHR (0.46) TSHRALDH1A1F7F3FAAH
SCHEMBL11229237 0.97 TSHR (0.46) TSHRALDH1A1F7F3FAAH
SCHEMBL8959959 0.97 TSHR (0.46) TSHRALDH1A1F7F3FAAH
SCHEMBL9801187 0.97 TSHR (0.46) TSHRALDH1A1F7F3FAAH
SCHEMBL9801308 0.94 TSHR (0.48) TSHRALDH1A1FAAHTRPV1THRB
SCHEMBL9801479 0.92 TSHR (0.52) TSHRALDH1A1FAAHTRPV1LMNA
SCHEMBL9801103 0.92 TSHR (0.52) TSHRALDH1A1FAAHTRPV1LMNA
SCHEMBL2945293 0.92 TSHR (0.52) TSHRALDH1A1FAAHTRPV1LMNA
SCHEMBL9788915 0.92 TSHR (0.52) TSHRALDH1A1FAAHTRPV1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9205232-B2 Balloon for catheter and balloon catheter TERUMO KABUSHIKI KAISHA (JP) 2015-12-08 US claimed
US-20130085519-A1 BALLOON FOR CATHETER AND BALLOON CATHETER TERUMO KABUSHIKI KAISHA (JP) 2013-04-04 US claimed
US-20240191009-A1 POLYFUNCTIONALIZED HIGH-CIS 1,4-POLYBUTADIENE AND METHOD FOR MANUFACTURING THE SAME KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2024-06-13 US disclosed
WO-2024071117-A1 BALLOON CATHETER テルモ株式会社 2024-04-04 WO disclosed
WO-2024071115-A1 MEDICAL LONG BODY, AND BALLOON CATHETER テルモ株式会社 2024-04-04 WO disclosed
US-20230099694-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2023-03-30 US disclosed
CN-109153653-B Novel compound, photocurable composition, cured product thereof, printing ink, and printed matter using the printing ink DIC株式会社 2022-06-28 CN disclosed
US-20220127403-A1 RUBBER POLYMER, METHOD FOR PREPARING THEREOF, AND RUBBER COMPOSITION COMPRISING THE SAME KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2022-04-28 US disclosed
US-20210052575-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2021-02-25 US disclosed
EP-2880033-B1 CYCLIC UREA- OR LACTAM-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND THE USES THEREOF PURDUE PHARMA LP (US) 2020-06-17 EP disclosed
US-20200061056-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2020-02-27 US disclosed
US-20040115162-A1 Dermatological preparations KAO CORPORATION (JP) 2004-06-17 US disclosed
US-6685953-B1 WATER RETENTION CAPACITY; MOISTURIZER; ALKOXYALKYAMIDES OF ALKYLENEDICARBOXYLIC ACIDS KAO CORPORATION (JP) 2004-02-03 US disclosed
EP-1166766-A1 EXTERNAL PREPARATION COMPOSITIONS Kao Corporation (JP) 2002-01-02 EP disclosed
EP-0498620-B1 Colored polyacetal resin composition POLYPLASTICS CO (JP) 1997-05-21 EP disclosed
US-5212222-A Nitrogen compound, fatty ester, salt, hindered phenol POLYPLASTICS CO., LTD. (JP) 1993-05-18 US disclosed
EP-0498620-A1 Colored polyacetal resin composition POLYPLASTICS CO. LTD. (JP) 1992-08-12 EP disclosed
US-4992150-A Telomer with alpha-olefin;oil and fuel additive NIPPON OIL CO, LTD. (JP) 1991-02-12 US disclosed
EP-0379014-A2 Polyarylene sulfides, process for preparation of the same, and resin compositions containing the same IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1990-07-25 EP disclosed
US-3996193-A POLYALKYLENEPOLYAMINES, DIOLEFIN RUBBER THE DOW CHEMICAL COMPANY (US) 1976-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230099694-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS SUZ12, BRPF3, BRD4 TSHR 1644/4885ALDH1A1 1257/4885F7 4585/4885
US-20210052575-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS SUZ12, SULT2A1, CYP4Z1 TSHR 1868/4885ALDH1A1 1445/4885F7 4618/4885
US-20200061056-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS SUZ12, BRPF3, BRD4 TSHR 1644/4885ALDH1A1 1257/4885F7 4585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.