Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6055618 | 0.84 | NR5A1 (0.45) | TSHRTP53LMNAMAPTKDM4E | |
| SCHEMBL1419943 | 0.81 | TSHR (0.40) | TSHRCA2CA1TP53LMNA | |
| SCHEMBL7596823 | 0.81 | TSHR (0.50) | TSHRCA2CA1TP53LMNA | |
| SCHEMBL1836371 | 0.80 | SLC6A2 (0.46) | TSHRTP53LMNAMEN1KMT2A | |
| SCHEMBL11377841 | 0.80 | CA12 (0.48) | TSHRCA2CA1TP53MEN1 | |
| SCHEMBL27980864 | 0.79 | ALDH1A1 (0.44) | TSHRCA2CA1TP53LMNA | |
| SCHEMBL7559302 | 0.79 | TSHR (0.52) | TSHRCA2CA1TP53LMNA | |
| SCHEMBL27752147 | 0.79 | TSHR (0.44) | TSHRCA2CA1TP53LMNA | |
| SCHEMBL9799537 | 0.78 | ALDH1A1 (0.47) | TSHRCA2CA1TP53MAPT | |
| SCHEMBL504371 | 0.78 | ALDH1A1 (0.47) | TSHRCA2CA1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320144-A | Fungicidal use of diphenyl esters of alkylenes | GAF CORPORATION (US) | 1982-03-16 | — | — | US | disclosed |