Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL11381182 | 1.00 | MAPT (0.50) | MAPTALDH1A1TDP1LMNABLM | |
| Ethylenediamine SCHEMBL8619347 | 1.00 | MAPT (0.50) | MAPTALDH1A1TDP1LMNABLM | |
| Ethylenediamine SCHEMBL28445890 | 1.00 | MAPT (0.50) | MAPTALDH1A1TDP1LMNABLM | |
| Ethylenediamine SCHEMBL1331588 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL338154 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL16761050 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL8414481 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL11440118 | 1.00 | MAPT (0.50) | MAPTALDH1A1TDP1LMNABLM | |
| Ethylenediamine SCHEMBL371485 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL1331073 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350614-A | NOBLE METAL OXIDE; MORE COMPLETE COMBUSTION OF COKE DURING REGENERATION | MOBIL OIL CORPORATION (US) | 1982-09-21 | — | — | US | disclosed |
| US-4282084-A | Catalytic cracking process | MOBIL OIL CORPORATION (US) | 1981-08-04 | — | — | US | disclosed |
| US-4174272-A | BURNING COKE DEPOSITED ON CATALYST DURING CRACKING IN PRESENCE OF DECOMPOSABLE PLATINUM GROUP METAL COMPOUND | MOBIL OIL CORPORATION (US) | 1979-11-13 | — | — | US | disclosed |
| US-4159239-A | DURING CATALYST REGENERATION TO COMBUST CARBON MONOXIDE TO CARBON DIOXIDE A GROUP 8 METAL IS ADDED | MOBIL OIL CORPORATION (US) | 1979-06-26 | — | — | US | disclosed |
| US-4093535-A | OF GAS OIL TO PRODUCE MOTOR FUEL, ACID CATALYST CONTAINING NOBLE METAL OXIDIZING COMPONENT FOR CONVERSION OF CARBON MONOXIDE DURING REGENERATION | MOBIL OIL CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |
| US-4072600-A | Catalytic cracking process | MOBIL OIL CORPORATION (US) | 1978-02-07 | — | — | US | disclosed |