Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL11381182 | 1.00 | MAPT (0.50) | MAPTALDH1A1TDP1LMNABLM | |
| Ethylenediamine SCHEMBL11229397 | 1.00 | MAPT (0.50) | MAPTALDH1A1TDP1LMNABLM | |
| Ethylenediamine SCHEMBL28445890 | 1.00 | MAPT (0.50) | MAPTALDH1A1TDP1LMNABLM | |
| Ethylenediamine SCHEMBL1331588 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL338154 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL16761050 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL8414481 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL11440118 | 1.00 | MAPT (0.50) | MAPTALDH1A1TDP1LMNABLM | |
| Ethylenediamine SCHEMBL371485 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL1331073 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240295038-A1 | METAL-IMPREGNATED CARBON MATERIALS | UNITED STATES DEPARTMENT OF ENERGY | 2024-09-05 | — | — | US | claimed |
| JP-10284541-A | — | — | None | — | — | JP | disclosed |
| US-20240295038-A1 | METAL-IMPREGNATED CARBON MATERIALS | UNITED STATES DEPARTMENT OF ENERGY | 2024-09-05 | — | — | US | disclosed |
| CN-115598185-A | Composite gas-sensitive material and preparation method and application thereof | 南方电网数字电网研究院有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| JP-H10284541-A | SUPPORTING SUBSTRATE, METHOD FOR PRODUCING SUPPORTING SUBSTRATE, ELECTRONIC COMPONENT DEVICE AND METHOD FOR SURFACE TREATING SUPPORTING SUBSTRATE | HITACHI CHEM CO LTD | 1998-10-23 | — | — | JP | disclosed |