Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3630554 | 0.79 | CYP1A2 (0.42) | CYP1A2HTT | |
| SCHEMBL894093 | 0.79 | — | — | |
| SCHEMBL3628981 | 0.73 | CYP1A2 (0.51) | CYP1A2HTT | |
| SCHEMBL3626372 | 0.70 | CYP1A2 (0.57) | CYP1A2 | |
| SCHEMBL10148202 | 0.69 | — | — | |
| SCHEMBL10290719 | 0.69 | — | — | |
| SCHEMBL4927326 | 0.69 | CYP1A2 (0.50) | CYP1A2 | |
| SCHEMBL893893 | 0.69 | CYP1A2 (0.76) | CYP1A2 | |
| SCHEMBL5022798 | 0.69 | CYP1A2 (0.50) | CYP1A2 | |
| SCHEMBL12359250 | 0.69 | ANPEP (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309348-A | DIURETICS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |
| US-4235901-A | TREATING HYPERTENSION IN MAMMALS WITH AN EFFECTIVE RENAL MINERALCORTICOID ANTAGONIST | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-11-25 | — | — | US | disclosed |
| WO-1979001037-A1 | 1-HYDROXYALKANAMINE PYRANO(3,4-B)INDOLE DERIVATIVES | AMERICAN HOME PROD (US) | 1979-11-29 | — | — | WO | disclosed |
| EP-0005365-A1 | Pyrano and thiopyrano (3,4-b) indole derivatives, processes for their preparation and pharmaceutical compositions containing them | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-11-14 | — | — | EP | disclosed |