Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749566 | 0.81 | CYP1A2 (0.39) | CYP1A2HTTLMNAMAPT | |
| SCHEMBL11229541 | 0.79 | CYP1A2 (0.47) | CYP1A2HTT | |
| SCHEMBL29368212 | 0.79 | CYP1A2 (0.38) | CYP1A2HTTKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL5643883 | 0.78 | — | — | |
| SCHEMBL3628636 | 0.78 | — | — | |
| SCHEMBL3628981 | 0.72 | CYP1A2 (0.51) | CYP1A2HTTMAPT | |
| SCHEMBL26300297 | 0.71 | CYP1A2 (0.39) | CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL3626372 | 0.69 | CYP1A2 (0.57) | CYP1A2 | |
| SCHEMBL8654222 | 0.69 | — | — | |
| SCHEMBL27575 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7695863-B2 | rechargeable batteries having excellent battery cycle properties, electrical capacity and storage characteristic during charging, comprising electrodes and a nonaqueous electrolytic solution containing a dicarbonyl compound as an additive | UBE INDUSTRIES, LTD. (JP) | 2010-04-13 | — | — | US | disclosed |
| US-20080102377-A1 | rechargeable batteries having excellent battery cycle properties, electrical capacity and storage characteristic during charging, comprising electrodes and a nonaqueous electrolytic solution containing a dicarbonyl compound as an additive | UBE INDUSTRIES, LTD (JP) | 2008-05-01 | — | — | US | disclosed |
| US-4309348-A | DIURETICS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |
| US-4235901-A | TREATING HYPERTENSION IN MAMMALS WITH AN EFFECTIVE RENAL MINERALCORTICOID ANTAGONIST | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-11-25 | — | — | US | disclosed |
| US-4179503-A | DIURETICS | AMERICAN HOME PRODUCTS CORP. (US) | 1979-12-18 | — | — | US | disclosed |
| WO-1979001037-A1 | 1-HYDROXYALKANAMINE PYRANO(3,4-B)INDOLE DERIVATIVES | AMERICAN HOME PROD (US) | 1979-11-29 | — | — | WO | disclosed |
| EP-0005365-A1 | Pyrano and thiopyrano (3,4-b) indole derivatives, processes for their preparation and pharmaceutical compositions containing them | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-11-14 | — | — | EP | disclosed |