Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805455 | 0.82 | KCNN4 (0.42) | KCNN4TSHRLMNAHTR2AHTR2C | |
| SCHEMBL5925963 | 0.80 | HTR2A (0.41) | KCNN4TSHRLMNAHTR2AHTR2C | |
| SCHEMBL16033653 | 0.80 | KCNN4 (0.41) | KCNN4TSHRLMNAHTR2AHTR2C | |
| SCHEMBL7414917 | 0.80 | TAAR1 (0.50) | KCNN4TSHRLMNAHTR2AHTR2C | |
| SCHEMBL18516974 | 0.78 | HTR2A (0.40) | KCNN4TSHRLMNAHTR2AHTR2C | |
| SCHEMBL9247746 | 0.78 | KCNN4 (0.39) | KCNN4TSHRLMNAHTR2AHTR2C | |
| SCHEMBL9130050 | 0.76 | KCNN4 (0.45) | KCNN4TSHRLMNAHTR2AHTR2C | |
| SCHEMBL294956 | 0.76 | ALDH1A1 (0.32) | TSHRALDH1A1TDP1TAAR1 | |
| SCHEMBL11516560 | 0.76 | ALDH1A1 (0.58) | TSHRLMNACYP1A2CYP2D6NFKB1 | |
| SCHEMBL294957 | 0.76 | CYP3A4 (0.38) | TSHRCYP1A2ALDH1A1TDP1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57154134-A | — | — | None | — | — | JP | disclosed |
| JP-S57154134-A | PREPARATION OF HALOGENONEOPHYL CHLORIDE | MITSUI TOATSU CHEM INC | 1982-09-22 | — | — | JP | disclosed |