Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2837734 | 0.79 | MAPT (0.55) | MAPTALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL27945575 | 0.78 | KMT2A (0.43) | MAPTALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL2218947 | 0.76 | ALDH1A1 (0.59) | MAPTALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL5712996 | 0.74 | ALDH1A1 (0.57) | MAPTALDH1A1LMNAKDM4ENPC1 | |
| Potassium Ion SCHEMBL11543057 | 0.74 | ALDH1A1 (0.57) | MAPTALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL5712997 | 0.74 | ALDH1A1 (0.57) | MAPTALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL11543051 | 0.74 | ALDH1A1 (0.57) | MAPTALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL2411244 | 0.73 | MAPT (0.57) | MAPTALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL522546 | 0.72 | MAPT (0.53) | MAPTALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL11237513 | 0.72 | MAPT (0.51) | MAPTALDH1A1LMNAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361450-A | Plastic bonded explosive compositions | THIOKOL CORPORATION (US) | 1982-11-30 | — | — | US | claimed |
| CN-118290423-A | 5, 6-Condensed pyrazole triazine and polynitrobenzene compounded high-energy-density material and synthesis method thereof | 南京理工大学 | 2024-07-05 | — | — | CN | disclosed |
| CN-118084791-A | High-energy-density compound based on polynitrobenzene bipyrazole and synthesis method thereof | 南京理工大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-103396374-A | Energetic compound 1,3,5-three(1H-1,2,4-triazolyl)-2,4,6-trinitrobenzene and synthetic method thereof | INST CHEMICAL MATERIAL CHINA ACADEMY ENGINEERING PHYSICS | 2013-11-20 | — | — | CN | disclosed |